Haemophilus parasusuis and E.coli fimbrial type F-18 are two diseases that strike in the nursery and take money out of your pocket, says Tom Fangman, a University of Missouri veterinarian.

Haemophilus parasuis transmission is believed to be vertical when the organism can be isolated from pigs' nasal passages at less than seven days of age. This organism cannot be successfully eliminated by a strict segregated-early weaning management program, says Fangman.

Prophylactic use of antibiotics or therapeutic feed/water medications may be of little value in severe Haemo-philus parasuis outbreaks. High doses of systemic antibiotics should be given as soon as clinical signs are observed, says Fangman. All pigs in the affected group should be treated, whether they exhibit clinical signs or not.

Penicillin was once considered the drug of choice, but an increasing resistance to penicillin has been reported, he notes. Eradication is not believed to be possible at this time.

E.coli fimbrial type F-18 is presumed to occur via aerosol transmission, feed, other vehicles, pigs and possibly other animals, like rats and mice.

Antibiotic therapy is limited as those organisms are highly resistant to antibiotics, says Fangman. Mucosal immunity and/or competitive exclusion methods will have to be explored in the future. Eradication of the disease is not possible at this time, he concludes.